SCHEMBL8375337

SCHEMBL8375337

O=C(ONCCCO)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 3/20 0.50
POLB P06746 2/20 0.50
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 4/20 0.47
TSHR P16473 2/20 0.47
LMNA P02545 2/20 0.45
F2 P00734 1/20 0.45
MAPK1 P28482 2/20 0.42
SLC6A3 Q01959 2/20 0.42
HIF1A Q16665 1/20 0.42
SLC6A2 P23975 1/20 0.42
PKM P14618 1/20 0.41
CASP3 P42574 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CYP4A11 Q02928 3/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10904247 0.89 KMT2A (0.53) KMT2AALDH1A1POLBMAPTTDP1
SCHEMBL27954014 0.89 ALDH1A1 (0.53) KMT2AALDH1A1POLBMAPTTDP1
Hydrochloric Acid SCHEMBL10904248 0.87 KMT2A (0.52) KMT2AALDH1A1POLBMAPTTDP1
Hydrochloric Acid SCHEMBL10905007 0.87 KMT2A (0.52) KMT2AALDH1A1POLBMAPTTDP1
SCHEMBL20093506 0.85 HTT (0.46) KMT2AALDH1A1POLBMAPTTDP1
SCHEMBL21155014 0.85 ALDH1A1 (0.46) KMT2AALDH1A1POLBMAPTTDP1
SCHEMBL3492807 0.84 LMNA (0.51) KMT2AALDH1A1POLBMAPTTDP1
SCHEMBL14541882 0.84 CA1 (0.48) KMT2AALDH1A1POLBTDP1TSHR
SCHEMBL18513315 0.84 HDAC1 (0.45) KMT2APOLBTSHRLMNAMEN1
SCHEMBL14974133 0.83 POLB (0.47) KMT2AALDH1A1POLBMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552289-A4 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN 1993-08-11 EP claimed
EP-0552289-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES INC. (US) 1993-07-28 EP claimed
WO-1992005769-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES, INC. (US) 1992-04-16 WO claimed
WO-1991017740-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF FLURBIPROFEN ANALGESIC ASSOCIATES (US) 1991-11-28 WO claimed
CN-102356121-A Uv and light protective film HUHTAMAKI FORCHHEIM 2012-02-15 CN disclosed
EP-0901512-A1 DETERGENT COMPOSITION UNILEVER PLC (GB) 1999-03-17 EP disclosed
WO-1997044422-A1 DETERGENT COMPOSITION UNILEVER PLC (GB) 1997-11-27 WO disclosed