Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375337 | 0.85 | KMT2A (0.50) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL10904247 | 0.84 | KMT2A (0.53) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL20093506 | 0.84 | HTT (0.46) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| Hydrochloric Acid SCHEMBL10905007 | 0.83 | KMT2A (0.52) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| Hydrochloric Acid SCHEMBL10904248 | 0.83 | KMT2A (0.52) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL26460865 | 0.83 | TDP1 (0.46) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL27954014 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL10061827 | 0.81 | KMT2A (0.57) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL3492807 | 0.80 | LMNA (0.51) | ALDH1A1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL14974133 | 0.79 | POLB (0.47) | ALDH1A1KMT2AMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10751419-B2 | Method for synthesis of reactive conjugate clusters | IONIS PHARMACEUTICALS, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190209694-A1 | METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS | IONIS PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10751419-B2 | Method for synthesis of reactive conjugate clusters | ACOT7, COASY, LCAT | ALDH1A1 1477/4885KMT2A 849/4885MAPT 1280/4885 |
| US-20190209694-A1 | METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS | ACOT7, COASY, LCAT | ALDH1A1 1477/4885KMT2A 849/4885MAPT 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.