Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arprinocid SCHEMBL8375355 | 0.88 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Arprinocid SCHEMBL31379008 | 0.88 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Arprinocid SCHEMBL31025603 | 0.88 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Arprinocid SCHEMBL126655 | 0.88 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL10962832 | 0.78 | ADORA2A (0.68) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11016348 | 0.78 | ADORA2A (0.63) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11812620 | 0.73 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11807952 | 0.73 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11462599 | 0.72 | SMN1; SMN2 (0.84) | LMNASMN1; SMN2HSD17B10ALDH1A1TSHR | |
| SCHEMBL11565162 | 0.72 | ALDH1A1 (0.56) | LMNASMN1; SMN2HSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916215-A | Transdermal microdosing delivery of hallucinogen derivatives | 长矛治疗股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-11607458-B2 | Enrichment-triggered chemical delivery system | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-03-21 | — | — | US | disclosed |
| CN-115038451-A | Multimodal compositions and methods of treatment | 阿奎斯蒂弗医疗股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115003279-A | Prodrug compositions and methods of treatment | 阿奎斯蒂弗医疗股份有限公司 | 2022-09-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11607458-B2 | Enrichment-triggered chemical delivery system | HMGB1, PAICS, CCL2 | PI4KA 2878/4885PI4K2B 3483/4885PI4K2A 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.