SCHEMBL8375387

SCHEMBL8375387

CCCCCCC(F)COc1ccccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 3/20 0.53
MEN1 O00255 2/20 0.53
RECQL P46063 1/20 0.53
ALDH1A1 P00352 3/20 0.52
NR1I2 O75469 1/20 0.50
LMNA P02545 1/20 0.50
CHRM2 P08172 1/20 0.50
CYP3A4 P08684 1/20 0.50
ADRA2A P08913 1/20 0.50
MAPT P10636 1/20 0.50
OPRK1 P41145 1/20 0.50
HTR2B P41595 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
PTPN11 Q06124 3/20 0.48
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
PTK2B Q14289 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8982668 0.86 KMT2A (0.56) KMT2AKDM4EMEN1RECQLALDH1A1
Hydrochloric Acid SCHEMBL8982638 0.85 KMT2A (0.55) KMT2AKDM4EMEN1RECQLALDH1A1
Hydrochloric Acid SCHEMBL8982703 0.85 KMT2A (0.55) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL10397367 0.84 KMT2A (0.53) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL16653945 0.83 KMT2A (0.54) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL9562079 0.82 ALDH1A1 (0.41) KMT2AKDM4EMEN1RECQLALDH1A1
Hydrochloric Acid SCHEMBL8982643 0.82 ALDH1A1 (0.53) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL9488200 0.81 LMNA (0.42) KMT2AMEN1NR1I2LMNACHRM2
Ammonia Solution, Strong SCHEMBL3453382 0.80 KMT2A (0.62) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL3665313 0.80 KMT2A (0.74) KMT2AKDM4EMEN1RECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626438-B1 Mesomorphic compound, liquid crystal composition and liquid crystal device CANON KK (JP) 1999-03-10 EP disclosed
US-5720898-A UNIFORM ALIGNMENT, SWITCHING CONTROL CANON KABUSHIKI KAISHA (JP) 1998-02-24 US disclosed
EP-0322703-B1 Mesomorphic compound, liquid crystal composition and liquid crystal device CANON KK (JP) 1995-08-30 EP disclosed
EP-0626438-A1 Mesomorphic compound, liquid crystal composition and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-11-30 EP disclosed
EP-0322703-A2 Mesomorphic compound, liquid crystal composition and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1989-07-05 EP disclosed