Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437435 | 0.85 | PRSS1 (0.47) | LMNAMAPTGAAJAK2HTR1A | |
| SCHEMBL9488066 | 0.84 | PPARG (0.37) | LMNAMAPTPPARGPRSS1PRSS2 | |
| SCHEMBL18038533 | 0.84 | HTR1A (0.49) | LMNAMAPTGAAJAK2HTR1A | |
| SCHEMBL8375387 | 0.81 | KMT2A (0.53) | LMNAMAPTPRSS1PRSS2PRSS3 | |
| SCHEMBL6346051 | 0.80 | LMNA (0.40) | LMNAMAPTGAAJAK2HTR1A | |
| SCHEMBL6441845 | 0.80 | LMNA (0.40) | LMNAMAPTGAAJAK2HTR1A | |
| SCHEMBL10583709 | 0.79 | HTR1A (0.41) | MAPTHTR1APPARGPRSS1PRSS2 | |
| SCHEMBL9148171 | 0.78 | LTA4H (0.49) | LMNAHTR1ANR1I2CHRM2CYP3A4 | |
| SCHEMBL9145900 | 0.78 | LTA4H (0.49) | LMNAHTR1ANR1I2CHRM2CYP3A4 | |
| SCHEMBL4859448 | 0.78 | JAK2 (0.38) | LMNAMAPTGAAJAK2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315958-B1 | OPTICALLY ACTIVE MESOMORPHIC COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | CANON KABUSHIKI KAISHA (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4917821-A | Optically active mesomorphic compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |