SCHEMBL8375405

SCHEMBL8375405

O=C(O)c1ccc(-c2ccc(C(=O)O)c([N+](=O)[O-])c2)cc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.52
MAPT P10636 2/20 0.52
KMT2A Q03164 2/20 0.52
POLB P06746 2/20 0.52
MEN1 O00255 1/20 0.52
DTYMK P23919 1/20 0.51
TSHR P16473 3/20 0.49
ALDH1A1 P00352 2/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX15 P16050 1/20 0.49
CASP6 P55212 1/20 0.48
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
CES2 O00748 1/20 0.46
ABCB1 P08183 1/20 0.46
KCNMA1 Q12791 1/20 0.46
ERN1 O75460 1/20 0.45
LMNA P02545 1/20 0.44
HNF4A P41235 1/20 0.44
ACMSD Q8TDX5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17177737 0.96 DTYMK (0.49) TDP1MAPTKMT2APOLBMEN1
SCHEMBL5193454 0.93 CRHBP (0.59) TDP1MAPTKMT2APOLBMEN1
SCHEMBL8960342 0.91 ERN1 (0.57) TDP1MAPTKMT2APOLBMEN1
SCHEMBL5196091 0.90 BCL2L1 (0.46) TDP1MAPTKMT2APOLBMEN1
SCHEMBL6225779 0.90 MCL1 (0.54) TDP1MAPTKMT2APOLBMEN1
Formaldehyde SCHEMBL27611540 0.90 CRHBP (0.56) MAPTKMT2APOLBMEN1DTYMK
SCHEMBL6224258 0.90 CYP1A2 (0.49) TDP1MAPTKMT2APOLBMEN1
SCHEMBL14428413 0.90 MAPT (0.64) TDP1MAPTKMT2APOLBMEN1
SCHEMBL5193889 0.88 EIF4E (0.48) TDP1MAPTKMT2APOLBMEN1
SCHEMBL10475570 0.88 CYP11B1 (0.46) TDP1MAPTKMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106048631-A Cleaning agent for electroless copper plating tank 许勤峰 2016-10-26 CN disclosed
CN-105800757-A Treatment agent for dye wastewater 徐伟鹏 2016-07-27 CN disclosed
EP-0615527-B1 ARAMID BLOCK COPOLYMERS DU PONT (US) 1999-03-17 EP disclosed
EP-0610379-B1 ARAMID BLOCK COPOLYMERS DU PONT (US) 1998-07-01 EP disclosed
EP-0615527-A1 ARAMID BLOCK COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-09-21 EP disclosed
US-5346985-A Drawable high tensile strength aramids E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-09-13 US disclosed
EP-0610379-A1 ARAMID BLOCK COPOLYMERS E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1994-08-17 EP disclosed
WO-1993011180-A1 ARAMID BLOCK COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-10 WO disclosed
US-5212258-A Tensile strenght E. I DU PONT DE NEMOURS AND COMPANY (US) 1993-05-18 US disclosed
US-5212257-A Aromatic diamines and aromatic dicarboxylic acids condensation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-18 US disclosed
WO-1993009161-A1 ARAMID BLOCK COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 WO disclosed