Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375405 | 0.91 | TDP1 (0.52) | ERN1CASP6TSHRTDP1LMNA | |
| SCHEMBL5193454 | 0.88 | CRHBP (0.59) | TSHRTDP1LMNAPOLBDTYMK | |
| Terephthalic Acid SCHEMBL15808957 | 0.88 | CASP6 (0.70) | CASP6TSHRTDP1LMNAHCAR3 | |
| SCHEMBL17177737 | 0.88 | DTYMK (0.49) | ERN1CASP6TSHRTDP1LMNA | |
| SCHEMBL842661 | 0.86 | CASP6 (0.72) | CASP6TSHRLMNAHCAR3POLB | |
| SCHEMBL145092 | 0.86 | CASP6 (0.72) | CASP6TSHRLMNAHCAR3POLB | |
| SCHEMBL30810715 | 0.86 | CASP6 (0.72) | CASP6TSHRLMNAHCAR3POLB | |
| SCHEMBL5196091 | 0.85 | BCL2L1 (0.46) | ERN1CASP6TSHRTDP1POLB | |
| Formaldehyde SCHEMBL27611540 | 0.85 | CRHBP (0.56) | TSHRLMNAPOLBDTYMKABCB1 | |
| SCHEMBL6225779 | 0.85 | MCL1 (0.54) | TSHRTDP1POLBDTYMKABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539243-B1 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIRAI HIDEFUMI (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5319134-A | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIDEFUMI HIRAI (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0539243-A2 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | Hirai, Hidefumi (JP) | 1993-04-28 | — | — | EP | disclosed |