Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.53 |
| ▸ | HNF4A | P41235 | 2/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.47 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193454 | 0.97 | CRHBP (0.59) | CRHBPCRHR2ACMSDHNF4AKCNMA1 | |
| SCHEMBL8375405 | 0.90 | TDP1 (0.52) | CRHBPCRHR2ACMSDHNF4AKCNMA1 | |
| SCHEMBL17177737 | 0.86 | DTYMK (0.49) | CRHBPCRHR2ACMSDHNF4AKCNMA1 | |
| SCHEMBL8960342 | 0.85 | ERN1 (0.57) | CRHBPCRHR2ABCB1ABCC1MEN1 | |
| SCHEMBL6225779 | 0.84 | MCL1 (0.54) | CRHBPCRHR2KCNMA1ABCB1MCL1 | |
| SCHEMBL6224258 | 0.84 | CYP1A2 (0.49) | CRHBPCRHR2KCNMA1ABCB1MEN1 | |
| SCHEMBL5196091 | 0.84 | BCL2L1 (0.46) | CRHBPCRHR2ACMSDHNF4AKCNMA1 | |
| SCHEMBL14283133 | 0.84 | ABCB1 (0.58) | CRHBPCRHR2ACMSDHNF4AKCNMA1 | |
| SCHEMBL27985266 | 0.83 | DTYMK (0.58) | CRHBPCRHR2ACMSDHNF4AKCNMA1 | |
| SCHEMBL6226141 | 0.83 | ERN1 (0.43) | CRHBPCRHR2ACMSDHNF4AKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1596247-A | Lactam derivatives as antagonists of the human 11CBY receptor | SMITHKLINE BEECHAM PLC (GB) | 2005-03-16 | — | — | CN | disclosed |