⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837684 | 0.80 | CA1 (0.33) | — | |
| SCHEMBL838046 | 0.80 | CA1 (0.33) | — | |
| SCHEMBL9622427 | 0.79 | LMNA (0.46) | — | |
| SCHEMBL9622151 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL9744669 | 0.77 | LMNA (0.43) | — | |
| SCHEMBL4528214 | 0.75 | — | — | |
| SCHEMBL11585547 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL4341315 | 0.69 | — | — | |
| SCHEMBL20438760 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL26567846 | 0.69 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904415-B1 | HYDROPHOBING MINERALS AND FILLER MATERIALS | DOW CORNING (US) | 2014-03-12 | — | — | EP | disclosed |
| US-8142856-B2 | Preparing hydrolyzate containing polysiloxanes by hydrolyzing hydrolysable silane or hydrolysable silane mixture in presence of acid hydrolysis catalyst andcombining polysiloxane hydrolyzate with mineral and/or filler and optionally with water and/or a catalyst for condensation of the hydrolyzate | DOW CORNING CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-20080286474-A1 | Hydrophobing Minerals and Filler Materials | DOW SILICONES CORPORATION | 2008-11-20 | — | — | US | disclosed |
| EP-1904415-A2 | HYDROPHOBING MINERALS AND FILLER MATERIALS | Dow Corning Corporation (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007009935-A2 | HYDROPHOBING MINERALS AND FILLER MATERIALS | DOW CORNING CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |
| US-5106959-A | Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents | RHONE-POULENC, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5099006-A | ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates | RHONE-POULENC INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-5017694-A | With silanol-type compounds | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5017695-A | With cerium ammonium nitrate and silanol-type compound | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0319384-A2 | Cerium hydrocarbonsilyloxydes and process for their manufacture | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319383-A2 | Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |