SCHEMBL837684

SCHEMBL837684

CC(C)CC[Si](O)(CCC(C)C)CCC(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6114441 0.81 LMNA (0.41) CA1TSHRLMNA
SCHEMBL838046 0.80 CA1 (0.33) CA1TSHRLMNA
SCHEMBL837546 0.80
SCHEMBL9621988 0.79 LMNA (0.46) LMNA
SCHEMBL9622638 0.77 LMNA (0.43) LMNA
SCHEMBL9744546 0.77 LMNA (0.43) LMNA
SCHEMBL11585547 0.72 LMNA (0.35) CA1LMNA
SCHEMBL20438760 0.69 LMNA (0.33) LMNA
SCHEMBL4341315 0.69
SCHEMBL26567846 0.69 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536767-A Supported chromium-based polyethylene catalyst and preparation method thereof 中国石油化工股份有限公司 2022-12-30 CN disclosed
CN-106749786-A A kind of polyethylene catalysts 佛山瑞箭体育器材有限公司 2017-05-31 CN disclosed
US-20150244028-A1 NONAQUEOUS SECONDARY CELL, AND FIRE-RETARDANT AGENT AND ADDITIVE FOR NONAQUEOUS SECONDARY CELL WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-27 US disclosed
EP-2821395-A2 Novel disulfonic acid ester as an additive for an electrolyte for a lithium secondary battery Wako Pure Chemical Industries, Ltd. (JP) 2015-01-07 EP disclosed
US-8716513-B2 Process for production of bis-quaternary ammonium salt, and novel intermediate WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-06 US disclosed
EP-1904415-B1 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING (US) 2014-03-12 EP disclosed
CN-102453154-B Organic chromium catalyst for ethylene polymerization and preparation method thereof CHINA PETROLEUM & CHEMICAL 2013-07-24 CN disclosed
CN-101223117-B Hydrophobing minerals and filler materials DOW CORNING 2013-03-27 CN disclosed
EP-2463266-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE Wako Pure Chemical Industries, Ltd. (JP) 2012-06-13 EP disclosed
US-20120130107-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2012-05-24 US disclosed
WO-2007009935-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed
US-5106959-A Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents RHONE-POULENC, INC. (US) 1992-04-21 US disclosed
US-5099006-A ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates RHONE-POULENC INC. (US) 1992-03-24 US disclosed
US-5017694-A With silanol-type compounds RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
US-5017695-A With cerium ammonium nitrate and silanol-type compound RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
EP-0324671-A2 Alkoxy-type derivatives of trivalent metals of group 3b, and their preparation RHONE-POULENC CHIMIE (FR) 1989-07-19 EP disclosed
EP-0319383-A2 Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed
EP-0319384-A2 Cerium hydrocarbonsilyloxydes and process for their manufacture RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed
EP-0123060-B1 ULTRAPURE CRYSTALLINE SILICA POLYMORPHS AND PROCESS FOR THE PREPARATION THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-04 EP disclosed
EP-0123060-A1 Ultrapure crystalline silica polymorphs and process for the preparation thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130107-A1 PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE ASS1, C1S, FHIT CA1 163/4885TSHR 689/4885ALDH1A1 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.