SCHEMBL838046

SCHEMBL838046

CC(C)CC[Si](O)(O)CCC(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL837684 0.80 CA1 (0.33) CA1TSHRLMNA
SCHEMBL837546 0.80
SCHEMBL9622601 0.79 LMNA (0.46) LMNA
SCHEMBL9622477 0.77 LMNA (0.43) LMNA
SCHEMBL9622620 0.77 LMNA (0.43) LMNA
SCHEMBL11585547 0.72 LMNA (0.35) CA1LMNA
SCHEMBL20438760 0.69 LMNA (0.33) LMNA
SCHEMBL26567846 0.69 LMNA (0.33) LMNA
SCHEMBL4341315 0.69
SCHEMBL6114441 0.69 LMNA (0.41) CA1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904415-B1 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING (US) 2014-03-12 EP disclosed
US-8142856-B2 Preparing hydrolyzate containing polysiloxanes by hydrolyzing hydrolysable silane or hydrolysable silane mixture in presence of acid hydrolysis catalyst andcombining polysiloxane hydrolyzate with mineral and/or filler and optionally with water and/or a catalyst for condensation of the hydrolyzate DOW CORNING CORPORATION (US) 2012-03-27 US disclosed
US-20080286474-A1 Hydrophobing Minerals and Filler Materials DOW SILICONES CORPORATION 2008-11-20 US disclosed
EP-1904415-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS Dow Corning Corporation (US) 2008-04-02 EP disclosed
WO-2007009935-A2 HYDROPHOBING MINERALS AND FILLER MATERIALS DOW CORNING CORPORATION (US) 2007-01-25 WO disclosed
US-5106959-A Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents RHONE-POULENC, INC. (US) 1992-04-21 US disclosed
US-5099006-A ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates RHONE-POULENC INC. (US) 1992-03-24 US disclosed
US-5017694-A With silanol-type compounds RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
US-5017695-A With cerium ammonium nitrate and silanol-type compound RHONE-POULENC, INC. (US) 1991-05-21 US disclosed
EP-0319384-A2 Cerium hydrocarbonsilyloxydes and process for their manufacture RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed
EP-0319383-A2 Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed