SCHEMBL8375501

SCHEMBL8375501

CC1=Cc2ccccc2C1[O]

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.34
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
HTR2A P28223 1/20 0.30
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28038419 0.77 LMNA (0.34) LMNAALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL8149969 0.76 LMNA (0.35) LMNAALDH1A1SMN1; SMN2TDP1TSHR
Hydrochloric Acid SCHEMBL1974791 0.76 CYP11B1 (0.33) LMNATSHRALOX12ACHECYP19A1
SCHEMBL813995 0.74 LMNA (0.33) LMNAALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL5090888 0.74 LMNA (0.33) LMNAALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL251288 0.74 DRD2 (0.41) LMNAALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL29458545 0.74 DRD2 (0.41) LMNAALDH1A1SMN1; SMN2TDP1TSHR
Lithium SCHEMBL9145416 0.73 DRD2 (0.40) LMNAALDH1A1SMN1; SMN2TDP1TSHR
SCHEMBL4689404 0.73 LMNA (0.32) LMNAALDH1A1SMN1; SMN2TDP1TSHR
Iodide SCHEMBL1539721 0.73 LMNA (0.32) LMNAALDH1A1SMN1; SMN2TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
US-6005116-A HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA SANKYO COMPANY, LIMITED (JP) 1999-12-21 US disclosed
EP-0885891-A1 ISOXAZOLE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 LMNA 2963/4885ALDH1A1 151/4885SMN1; SMN2 3268/4885
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL CBR1, HAO2, CBR3 LMNA 2963/4885ALDH1A1 151/4885SMN1; SMN2 3268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.