Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL440498 | 0.96 | — | — | |
| Acetic Acid SCHEMBL6288674 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNCA2KDM4E | |
| Sulfuric Acid SCHEMBL6727153 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNCA2KDM4E | |
| Sulfuric Acid SCHEMBL28090965 | 0.88 | FFAR3 (0.58) | FFAR3LCKFYNCA2KDM4E | |
| Sulfuric Acid SCHEMBL1993694 | 0.85 | FFAR3 (0.54) | FFAR3LCKFYNCA2KDM4E | |
| Sulfuric Acid SCHEMBL27575264 | 0.85 | FFAR3 (0.54) | FFAR3LCKFYNCA2KDM4E | |
| Bicarbonate SCHEMBL7692947 | 0.84 | — | — | |
| Sulfuric Acid SCHEMBL164130 | 0.84 | FFAR3 (0.64) | FFAR3LCKFYNCA2KDM4E | |
| Acetone SCHEMBL2586373 | 0.84 | — | — | |
| Sulfuric Acid SCHEMBL10378486 | 0.84 | FFAR3 (0.64) | FFAR3LCKFYNCA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547162-B1 | PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME | EXXON CHEMICAL PATENTS INC (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5334671-A | Protective coating | EXXON CHEMICAL PATENTS INC. (US) | 1994-08-02 | — | — | US | disclosed |
| US-5326831-A | COATINGS | EXXON CHEMICAL PATENTS INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0547162-A1 | PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME | EXXON CHEMICAL PATENTS INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5210155-A | Coatings and paints; hardness, high impact strength, corrosion resistance, weatherproof, solvent resistance | EXXON CHEMICAL PATENTS INC. (US) | 1993-05-11 | — | — | US | disclosed |
| WO-1992003492-A1 | PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME | EXXON CHEMICAL PATENTS INC. (US) | 1992-03-05 | — | — | WO | disclosed |