Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.57 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.57 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 10/20 | 0.50 |
| ▸ | CA1 | P00915 | 10/20 | 0.50 |
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 10/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376183 | 1.00 | P4HB (0.57) | P4HBPDIA4PDIA3SLC28A3PRKCA | |
| SCHEMBL8654501 | 0.96 | P4HB (0.61) | P4HBPDIA4PDIA3SLC28A3CA12 | |
| SCHEMBL1726710 | 0.96 | P4HB (0.61) | P4HBPDIA4PDIA3SLC28A3CA12 | |
| SCHEMBL12651652 | 0.92 | P4HB (0.59) | P4HBPDIA4PDIA3PRKCAAKT1 | |
| SCHEMBL12651802 | 0.92 | P4HB (0.59) | P4HBPDIA4PDIA3PRKCAAKT1 | |
| SCHEMBL12651491 | 0.87 | P4HB (0.63) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL12651482 | 0.87 | P4HB (0.63) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL8108900 | 0.87 | TSHR (0.54) | P4HBPDIA4PDIA3PRKCAAKT1 | |
| SCHEMBL20633976 | 0.86 | P4HB (0.61) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL13324379 | 0.85 | P4HB (0.59) | P4HBPDIA4PDIA3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684254-B1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0684254-A1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |