Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376198 | 1.00 | ALDH1A1 (0.39) | ALDH1A1ALOX15NPC1SMN1; SMN2MAOB | |
| SCHEMBL8374758 | 0.82 | CES2 (0.48) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL9233541 | 0.78 | CES2 (0.41) | ALDH1A1ALOX15NPC1SMN1; SMN2HPGD | |
| SCHEMBL9233543 | 0.78 | CES2 (0.41) | ALDH1A1ALOX15NPC1SMN1; SMN2HPGD | |
| SCHEMBL18938482 | 0.72 | MAOB (0.38) | ALDH1A1ALOX15NPC1SMN1; SMN2MAOB | |
| SCHEMBL23731404 | 0.72 | CES2 (0.39) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL19900564 | 0.72 | CES2 (0.39) | ALDH1A1ALOX15CES2CES1GAA | |
| SCHEMBL18938855 | 0.71 | MEN1 (0.41) | ALDH1A1NPC1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL899003 | 0.70 | MEN1 (0.41) | ALDH1A1NPC1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL899002 | 0.70 | MEN1 (0.41) | ALDH1A1NPC1SMN1; SMN2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635499-B1 | Novel acaricidally active tetrazine derivatives | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1999-03-03 | — | — | EP | disclosed |
| US-5455237-A | Larvicides, ovicides | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-10-03 | — | — | US | disclosed |
| EP-0635499-A2 | Novel acaricidally active tetrazine derivatives | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1995-01-25 | — | — | EP | disclosed |