Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.58 |
| ▸ | ACHE | P22303 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723898 | 0.91 | CARM1 (0.67) | CARM1ACHEALDH1A1MAPTMAPK1 | |
| SCHEMBL11723894 | 0.91 | CARM1 (0.67) | CARM1ACHEALDH1A1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL11721656 | 0.89 | CARM1 (0.65) | CARM1ACHEALDH1A1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL11721663 | 0.89 | CARM1 (0.65) | CARM1ACHEALDH1A1MAPTMAPK1 | |
| Diethylamine SCHEMBL8780594 | 0.87 | ACHE (0.67) | CARM1ACHEALDH1A1MAPTMAPK1 | |
| Diethylamine SCHEMBL8377307 | 0.85 | MAPT (0.55) | ACHEALDH1A1MAPTMAPK1KMT2A | |
| Diethylamine SCHEMBL8377295 | 0.84 | MAPT (0.55) | ACHEALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL8376245 | 0.81 | CARM1 (0.57) | CARM1ACHEALDH1A1MAPTMAPK1 | |
| SCHEMBL29857531 | 0.81 | ALDH1A1 (0.64) | CARM1ACHEALDH1A1MAPTMAPK1 | |
| Diethylamine SCHEMBL8780601 | 0.79 | ALDH1A1 (0.52) | ACHEALDH1A1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636939-B1 | Photoinitiator compositions and photosensitive materials using the same | HITACHI CHEMICAL CO LTD (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5811218-A | IMPROVED PHOTOSENSITIVITY FOR MATERIALS CONTAINING POLYAMIC ACID AND ADDITION POLYMERIZABLE COMPOUND USED FOR PATTERN FORMATION | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0636939-A2 | Photoinitiator compositions and photosensitive materials using the same | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |