Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16537885 | 0.84 | MMP1 (0.40) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL2714777 | 0.79 | MMP1 (0.34) | ALDH1A1CYP2D6CYP2C9CYP2C19TDP1 | |
| SCHEMBL6930150 | 0.79 | MMP1 (0.34) | TSHRMMP1MMP2MMP3 | |
| SCHEMBL5859731 | 0.78 | LAP3 (0.34) | CYP2D6CYP2C9CYP2C19MMP1MMP2 | |
| SCHEMBL2639544 | 0.75 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL418898 | 0.75 | PPARD (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL776263 | 0.74 | LAP3 (0.36) | ALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL6890646 | 0.73 | GAA (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9579534 | 0.73 | GAA (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8910013 | 0.73 | LAP3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5898059-A | REACTING A DI(C1-C4)ALKYL TEREPHTHALATE WITH ETHYLENE GLYCOL TO YIELD BIS(2-HYDROXYETHYL) TEREPHTHALATE, ADDING A PHOSPHORUS SEQUESTERING AGENT AND POLYCONDENSING TO PRODUCE THE ARTICLES WITH LOW PARTICLE CONTENT, SMOOTH SURFACE | HOECHST DIAFOIL COMPANY (US) | 1999-04-27 | — | — | US | disclosed |
| EP-0864596-A1 | Process for the production of polyethylene terephthalate | Hoechst Diafoil GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |