Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859731 | 0.83 | LAP3 (0.34) | LAP3METAP1 | |
| SCHEMBL6930150 | 0.77 | MMP1 (0.34) | LAP3METAP1 | |
| SCHEMBL2714777 | 0.77 | MMP1 (0.34) | LAP3METAP1 | |
| SCHEMBL2118428 | 0.76 | LAP3 (0.38) | LAP3METAP1 | |
| SCHEMBL776263 | 0.76 | LAP3 (0.36) | LAP3METAP1 | |
| Hydrochloric Acid SCHEMBL13269112 | 0.75 | LAP3 (0.37) | LAP3METAP1 | |
| SCHEMBL16537885 | 0.74 | MMP1 (0.40) | — | |
| SCHEMBL1251447 | 0.74 | PPARD (0.35) | LAP3METAP1 | |
| SCHEMBL11745106 | 0.74 | LAP3 (0.34) | LAP3METAP1 | |
| SCHEMBL787731 | 0.73 | ALDH1A1 (0.39) | LAP3METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637720-A | Intermediate for (E)-4-[[3-[2-(4-cycloalkyl-2-thiazolyl)ethenyl]phenyl]amino-2,2-alkyldiyl-4-oxobutanoic acids | HOFFMANN-LA ROCHE INC. (US) | 1997-06-10 | — | — | US | disclosed |
| WO-1996008479-A1 | A PROCESS OF MAKING (E)-4-[3-[2-(4-CYCLOALKYL-2-THIAZOLYL)ETHENYL]PHENYL]AMINO-2,2-ALKYLDIYL-4-OXOBUTANOIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 1996-03-21 | — | — | WO | disclosed |