Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380076 | 0.83 | TDP2 (0.31) | — | |
| SCHEMBL18241908 | 0.74 | SMN1; SMN2 (0.35) | TAS1R3TAS1R1 | |
| SCHEMBL5610172 | 0.73 | ESR1 (0.43) | — | |
| SCHEMBL5610196 | 0.72 | TP53 (0.35) | TAS1R3TAS1R1 | |
| SCHEMBL9770066 | 0.70 | GPR84 (0.34) | — | |
| SCHEMBL17785969 | 0.68 | TP53 (0.45) | TAS1R3TAS1R1 | |
| SCHEMBL11296786 | 0.68 | ADRA2A (0.34) | — | |
| SCHEMBL17968474 | 0.68 | CYP1A2 (0.33) | — | |
| SCHEMBL28471511 | 0.67 | PDE2A (0.41) | — | |
| SCHEMBL18242272 | 0.67 | CA1 (0.37) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |