Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150359 | 0.92 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9151651 | 0.91 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9152695 | 0.91 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL7910603 | 0.91 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9151076 | 0.91 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9151358 | 0.91 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9151591 | 0.88 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8153271 | 0.87 | TSHR (0.57) | MAPTALDH1A1HSD17B10TSHRCYP11B1 | |
| SCHEMBL10359182 | 0.86 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL8155805 | 0.85 | HSD17B10 (0.60) | MAPTKDM4EALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| WO-1991005029-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-18 | — | — | WO | disclosed |