Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585107 | 0.94 | LMNA (0.56) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL8379792 | 0.86 | LMNA (0.51) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL11282985 | 0.85 | LMNA (0.55) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL622239 | 0.84 | LMNA (0.54) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL8377190 | 0.84 | LMNA (0.49) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL8859056 | 0.83 | LMNA (0.53) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL8743127 | 0.83 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8743319 | 0.83 | LMNA (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL23039434 | 0.83 | LMNA (0.55) | LMNACYP2C19HIF1AMAP2K1MAP2K2 | |
| SCHEMBL5028753 | 0.82 | LMNA (0.57) | LMNACYP2C19HIF1AMAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233249-B1 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA | COOK IMAGING CORP (US) | 1993-11-24 | — | — | EP | disclosed |
| US-4954348-A | Non-ionic polyol contrast media from ionic contrast media | COOK IMAGING CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0233249-A4 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA. | COOK MANAGING INC (US) | 1988-10-06 | — | — | EP | disclosed |
| EP-0233249-A1 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA. | COOK MANAGING INC (US) | 1987-08-26 | — | — | EP | disclosed |
| WO-1987000757-A1 | NON-IONIC POLYOL CONTRAST MEDIA FROM IONIC CONTRAST MEDIA | COOK IMAGING, INC. (US) | 1987-02-12 | — | — | WO | disclosed |