Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290214 | 1.00 | MAOB (0.49) | MAOBRAB9AMMP13ADAMTS4NPC1 | |
| SCHEMBL27830644 | 0.81 | SLC7A5 (0.47) | — | |
| SCHEMBL403906 | 0.80 | RAB9A (0.45) | MAOBRAB9AMMP13ADAMTS4NPC1 | |
| SCHEMBL27757196 | 0.79 | KMT2A (0.56) | MAOBL3MBTL1HTTTSHRGAA | |
| SCHEMBL1706675 | 0.79 | KMT2A (0.56) | MAOBL3MBTL1HTTTSHRGAA | |
| SCHEMBL799863 | 0.79 | CYP2A6 (0.52) | MAOBRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL138281 | 0.79 | KMT2A (0.56) | MAOBL3MBTL1HTTTSHRGAA | |
| SCHEMBL138280 | 0.79 | KMT2A (0.56) | MAOBL3MBTL1HTTTSHRGAA | |
| SCHEMBL23729269 | 0.78 | MAOB (0.50) | MAOBRAB9AMMP13ADAMTS4NPC1 | |
| SCHEMBL5998701 | 0.78 | RXRA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |