Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1369041 | 0.85 | TSHR (0.72) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL9974613 | 0.81 | — | — | |
| SCHEMBL12811584 | 0.81 | CYP3A4 (0.54) | ALDH1A1TSHRCYP3A4TP53TDP1 | |
| SCHEMBL11647259 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL14934973 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL4055518 | 0.77 | CYP3A4 (0.77) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL15479076 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL28237157 | 0.74 | CTSA (0.40) | ALDH1A1TSHR | |
| SCHEMBL194036 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL17333478 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 511 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027098-A | Prodrugs of ospirimol and derivatives thereof, and preparation method and application thereof | 珠海安哲医药科技有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-112979860-A | Wear-resistant flame-retardant organic glass plate and preparation method thereof | 安徽新涛光电科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-112538226-A | Flame-retardant PMMA light diffusion plate and preparation method thereof | 安徽新涛光电科技有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-108325560-B | Catalyst, preparation method thereof and method for preparing 3-hydroxy propionaldehyde | 万华化学集团股份有限公司 | 2020-09-08 | — | — | CN | claimed |
| CN-111286418-A | Plane grinding cleaning agent and preparation method thereof | 苏州衍生生物科技有限公司 | 2020-06-16 | — | — | CN | claimed |
| CN-108325560-A | A kind of catalyst and preparation method thereof and the method for preparing 3-HPA | 万华化学集团股份有限公司 | 2018-07-27 | — | — | CN | claimed |
| EP-2448950-A1 | SYNTHESIS OF N4- (2, 2-DIMETHYL-4- [ (DIHYDROGEN PHOSPHONOXY]-3-OXO-5-PYRIDO [1, 4]OXAZIN-6-YL)-5-FLUORO-N2- (3, 4, 5,-TRIMETHOXYPHENYL) -2, 4- PYRIMIDINEDIAMINE DISODIUM SALT | Rigel Pharmaceuticals, Inc. (US) | 2012-05-09 | — | — | EP | claimed |
| WO-2011002999-A1 | SYNTHESIS OF N4- (2, 2-DIMETHYL-4- [ (DIHYDROGEN PHOSPHONOXY ] -3-OXO-5-PYRIDO [1, 4] OXAZIN-6-YL)-5-FLUORO-N2- (3, 4, 5,-TRIMETHOXYPHENYL) -2, 4- PYRIMIDINEDIAMINE DISODIUM SALT | RIGEL PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | WO | claimed |
| JP-7292152-A | — | — | None | — | — | JP | disclosed |
| CN-119899510-A | Modified polycarbonate material, preparation method thereof and explosion-proof flame-retardant composite material | 北京航玻新材料技术有限公司 | 2025-04-29 | — | — | CN | disclosed |
| EP-4486455-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-111094258-B | Diazole compound and agricultural/horticultural fungicide | 日本曹达株式会社 | 2024-11-08 | — | — | CN | disclosed |
| CN-118843629-A | Antiviral compounds and methods of making and using the same | 吉利德科学公司 | 2024-10-25 | — | — | CN | disclosed |
| US-20240287108-A1 | nSMASE2 INHIBITOR PRODRUGS WITH ENHANCED ORAL AND BRAIN EXPOSURES | THE JOHNS HOPKINS UNIVERSITY | 2024-08-29 | — | — | US | disclosed |
| EP-1485085-A1 | PHOSPHATE PRODRUGS OF FLUOROOXINDOLES | Bristol-Myers Squibb Company (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20030195169-A1 | Phosphate prodrugs of fluorooxindoles | BRISTOL-MYERS SQUIBB COMPANY | 2003-10-16 | — | — | US | disclosed |
| WO-2003080047-A1 | PHOSPHATE PRODRUGS OF FLUOROOXINDOLES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
| US-6362172-B2 | (DIHYDROGEN PHOSPHONOXY)ALKYLOXY CONTAINING A TRIAZOLE DERIVATIVE USED AS ANTIFUNGAL AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-5747569-A | (METH)ACRYLATE ESTER WITH (METH)ACRYLIC ACID AND PHOSPHOROUS COMPOUND FOR FIRE RETARDANT CAST PANELS | ATOHAAS HOLDING C.V. (NL) | 1998-05-05 | — | — | US | disclosed |
| JP-H07292152-A | FLAME PROOFING AGENT COMPOSITION FOR FOAMED RESIN | FUJIMASU JIRO | 1995-11-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287108-A1 | nSMASE2 INHIBITOR PRODRUGS WITH ENHANCED ORAL AND BRAIN EXPOSURES | SGMS2, SMPD2, CERS2 | ALDH1A1 3493/4885TSHR 4859/4885CYP3A4 2221/4885 |
| US-20030195169-A1 | Phosphate prodrugs of fluorooxindoles | KCNA5, KCNN3, CACNA1E | ALDH1A1 1617/4885TSHR 1959/4885CYP3A4 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.