Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374414 | 0.93 | LMNA (0.34) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL8375513 | 0.91 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL8905997 | 0.91 | LMNA (0.38) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL8379840 | 0.90 | LMNA (0.39) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL17124727 | 0.90 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL8741511 | 0.89 | LMNA (0.39) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL28880451 | 0.88 | LMNA (0.43) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL8377049 | 0.87 | LMNA (0.36) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL7056140 | 0.87 | LMNA (0.46) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL12871782 | 0.87 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958376-A | Iodinated X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5958375-A | Urea-linked, iodinated bis phenyl compounds for X-ray contrast media | NYCOMED IMAGING AS (NO) | 1999-09-28 | — | — | US | disclosed |
| US-5882628-A | Contrast media | NYCOMED IMAGING AS (NO) | 1999-03-16 | — | — | US | disclosed |