SCHEMBL8378302

SCHEMBL8378302

O=C(c1cccc(Cl)c1)n1cccn1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.68
F2 P00734 2/20 0.68
PLAU P00749 2/20 0.68
KLKB1 P03952 2/20 0.68
PDE4B Q07343 4/20 0.58
PKM P14618 1/20 0.50
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.48
PARP1 P09874 1/20 0.47
ALDH1A1 P00352 1/20 0.46
MGAM O43451 1/20 0.46
AMY1A P0DUB6 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7949518 0.81 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B
SCHEMBL6016104 0.81 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B
SCHEMBL8376914 0.81 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B
SCHEMBL135362 0.79 ELANE (0.60) ELANEF2PLAUKLKB1PDE4B
SCHEMBL27931328 0.78 ELANE (0.56) ELANEF2PLAUKLKB1PDE4B
SCHEMBL6003843 0.74 ELANE (0.52) ELANEF2PLAUKLKB1PKM
SCHEMBL6272236 0.73 ELANE (0.54) ELANEF2PLAUKLKB1PKM
SCHEMBL11507719 0.72 PKM (0.48) ELANEPKMPARP1ALDH1A1MGAM
SCHEMBL27947555 0.72 KMO (0.60) ELANEF2PLAUKLKB1PDE4B
SCHEMBL11848471 0.71 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962690-A HERBICIDES DOW AGROSCIENCES LLC (US) 1999-10-05 US disclosed
US-5824802-A POSTEMERGENT HERBICIDE FOR CORN, WHEAT, BARLEY, RICE DOW AGROSCIENCES LLC (US) 1998-10-20 US disclosed