SCHEMBL135362

SCHEMBL135362

O=C(c1ccccc1)n1cccn1

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.60
F2 P00734 4/20 0.60
PLAU P00749 4/20 0.60
KLKB1 P03952 3/20 0.60
PDE4B Q07343 9/20 0.55
ALDH1A1 P00352 1/20 0.51
ALOX15 P16050 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11848471 0.83 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B
SCHEMBL6272236 0.82 ELANE (0.54) ELANEF2PLAUKLKB1ALDH1A1
SCHEMBL8378302 0.79 ELANE (0.68) ELANEF2PLAUKLKB1PDE4B
SCHEMBL6016104 0.79 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B
SCHEMBL8376914 0.79 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B
SCHEMBL7949518 0.79 ELANE (0.59) ELANEF2PLAUKLKB1PDE4B
SCHEMBL27931328 0.77 ELANE (0.56) ELANEF2PLAUKLKB1PDE4B
SCHEMBL28938168 0.76 ELANE (0.42) ELANEF2PLAUKLKB1PDE4B
SCHEMBL9350733 0.76 NOS1 (0.50) ELANEF2PLAUKLKB1PDE4B
SCHEMBL6270074 0.76 L3MBTL1 (0.56) ELANEF2PLAUKLKB1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-05-14 US claimed
US-20250064792-A1 MUSCLE REGENERATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-02-27 US claimed
CN-116120234-B Benzoyl pyrazole compound and application thereof 沈阳中化农药化工研发有限公司 2024-12-17 CN claimed
EP-4456711-A1 HPPD INHIBITOR HERBICIDE TOLERANT PLANT Advanta Holdings BV (NL) 2024-11-06 EP claimed
US-20240216353-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-07-04 US claimed
CN-117882730-A Bi-component weeding composition containing HPPD inhibitor and preparation method thereof 南通江山农药化工股份有限公司 2024-04-16 CN claimed
WO-2023126317-A1 HPPD INHIBITOR HERBICIDE TOLERANT PLANT Advanta Holdings B.V. (NL) 2023-07-06 WO claimed
US-20230203523-A1 HPPD INHIBITOR HERBICIDE TOLERANT PLANT Advanta Holdings B.V. (NL) 2023-06-29 US claimed
CN-116217487-A Benzoyl pyrazole compound and application thereof 沈阳中化农药化工研发有限公司 2023-06-06 CN claimed
CN-116120234-A Benzoyl pyrazole compound and application thereof 沈阳中化农药化工研发有限公司 2023-05-16 CN claimed
US-6010981-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-01-04 US claimed
CN-1224420-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 1999-07-28 CN claimed
WO-1999026930-A2 BENZYLIDENE PYRAZOLONES AND USE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-06-03 WO claimed
EP-0918755-A1 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES Dow AgroSciences LLC (US) 1999-06-02 EP claimed
EP-0914317-A2 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES Dow AgroSciences LLC (US) 1999-05-12 EP claimed
WO-1998052926-A2 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 1998-11-26 WO claimed
WO-1998042678-B1 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES 1998-11-26 WO claimed
US-5824802-A POSTEMERGENT HERBICIDE FOR CORN, WHEAT, BARLEY, RICE DOW AGROSCIENCES LLC (US) 1998-10-20 US claimed
WO-1998042678-A1 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 1998-10-01 WO claimed
CN-86103671-A HERBICIDAL COMPOSITIONS 1986-12-17 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260130899-A1 METHOD OF TREATMENT FOR PREVENTION OF GLUCOCORTICOID TOXICITY AND/OR ENHANCEMENT OF MUSCLE REGENERATION VIA NEUTROPHIL ELASTASE INHIBITION SERPINB1, ELANE, CELA1 ELANE 2/4885F2 1939/4885PLAU 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.