SCHEMBL8378346

SCHEMBL8378346

CCN(CC)c1nc(-c2ccccc2)cs1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.54
KMT2A Q03164 5/20 0.54
NPC1 O15118 5/20 0.54
MEN1 O00255 4/20 0.54
MAPT P10636 3/20 0.54
LMNA P02545 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
TSHR P16473 2/20 0.54
TP53 P04637 2/20 0.54
NFKB1 P19838 2/20 0.54
NFKB2 Q00653 2/20 0.54
RELA Q04206 2/20 0.54
USP2 O75604 1/20 0.54
HPGD P15428 1/20 0.54
MAPK1 P28482 1/20 0.54
MMP13 P45452 1/20 0.54
HSD17B10 Q99714 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ALDH1A1 P00352 5/20 0.50
GSTO1 P78417 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18674609 0.93 RAB9A (0.51) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL20243238 0.91 KMT2A (0.49) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL18678147 0.88 ATP4A (0.50) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL18674583 0.87 GSTO1 (0.60) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL18674603 0.85 RAB9A (0.58) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL18387683 0.85 RAB9A (0.56) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL18674657 0.84 KMT2A (0.53) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL8137225 0.84 RAB9A (0.52) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL1744722 0.83 KMT2A (0.55) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL30662150 0.82 RAB9A (0.54) RAB9AKMT2ANPC1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4505857-A DISPERSE DYES FOR TEXTILE DYEING; COLORFASTNESS SANDOZ LTD. (CH) 1985-03-19 US claimed
US-9993409-B2 Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler L'OREAL (FR) 2018-06-12 US disclosed
US-9993409-B2 Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler L'OREAL (FR) 2018-06-12 US disclosed
US-20170087075-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER L'OREAL (FR) 2017-03-30 US disclosed
US-20170087075-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER L'OREAL (FR) 2017-03-30 US disclosed
US-8741508-B2 Colored curable composition, color resist, ink-jet ink, color filter and method for producing the same, solid-state image pickup device, image display device, liquid crystal display, organic el display, and colorant compound and tautomer thereof FUJIFILM CORPORATION (JP) 2014-06-03 US disclosed
US-8741508-B2 Colored curable composition, color resist, ink-jet ink, color filter and method for producing the same, solid-state image pickup device, image display device, liquid crystal display, organic el display, and colorant compound and tautomer thereof FUJIFILM CORPORATION (JP) 2014-06-03 US disclosed
US-20120021354-A1 COLORED CURABLE COMPOSITION, COLOR RESIST, INK-JET INK, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID-STATE IMAGE PICKUP DEVICE, IMAGE DISPLAY DEVICE, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, AND COLORANT COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120021354-A1 COLORED CURABLE COMPOSITION, COLOR RESIST, INK-JET INK, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID-STATE IMAGE PICKUP DEVICE, IMAGE DISPLAY DEVICE, LIQUID CRYSTAL DISPLAY, ORGANIC EL DISPLAY, AND COLORANT COMPOUND AND TAUTOMER THEREOF FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
EP-0742811-B1 METHOD FOR PREPARING PYRIDINE DYES BASF AG (DE) 1999-03-31 EP disclosed
EP-0269953-A2 Thiophene azo dyes BASF Aktiengesellschaft (DE) 1988-06-08 EP disclosed
EP-0247618-A2 Trisazo dyes containing heterocycles BASF Aktiengesellschaft (DE) 1987-12-02 EP disclosed
US-4694075-A DISAZO DYES FOR PAPER BASF AKTIENGESELLSCHAFT (DE) 1987-09-15 US disclosed
EP-0189836-A1 Basic azo dyes BASF Aktiengesellschaft (DE) 1986-08-06 EP disclosed
EP-0100018-B1 PROCESS FOR THE PRODUCTION OF 2-N,N-DISUBSTITUTED AMINOTHIAZOLES BASF Aktiengesellschaft (DE) 1986-04-02 EP disclosed
EP-0169483-A2 Heterocyclic azo dyes BASF Aktiengesellschaft (DE) 1986-01-29 EP disclosed
US-4562248-A YELLOW OR ORANGE SHADES ON HYDROPHOBIC FIBERS EASTMAN KODAK COMPANY (US) 1985-12-31 US disclosed
US-4560751-A CYCLIZATION OF AMIDO-THIOAMIDE COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1985-12-24 US disclosed
EP-0100018-A1 Process for the production of 2-N,N-disubstituted aminothiazoles BASF Aktiengesellschaft (DE) 1984-02-08 EP disclosed
EP-0015512-A1 Thiazole dispersion dyestuffs BASF Aktiengesellschaft (DE) 1980-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170087075-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER KRT18, F12, CBR3 RAB9A 3590/4885KMT2A 561/4885NPC1 4834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.