Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378557 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8377998 | 0.80 | HSD17B10 (0.40) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8377997 | 0.80 | HSD17B10 (0.40) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8896790 | 0.79 | NPC1 (0.47) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8896803 | 0.79 | NPC1 (0.47) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL9600369 | 0.77 | SMN1; SMN2 (0.45) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL4611278 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5298283 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL9055334 | 0.73 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL34463646 | 0.73 | MAPT (0.49) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919939-A | Preparation of cephem and isooxacephem derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-07-06 | — | — | US | disclosed |
| US-5883247-A | ACYLATION WITH AMINOTHIAZOLE DERIVATIVE ACTIVATED AS MIXED ANHYDRIDE OF THIOPHOSPHORIC ACID | HOFFMANN-LA ROCHE INC. (US) | 1999-03-16 | — | — | US | disclosed |