Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4B | O94953 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377998 | 1.00 | HSD17B10 (0.40) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL8378561 | 0.80 | ALDH1A1 (0.49) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL8378557 | 0.80 | ALDH1A1 (0.49) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL2789164 | 0.74 | GABRA5 (0.51) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL3999942 | 0.74 | GABRA5 (0.51) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8913011 | 0.73 | GABRA5 (0.50) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL8526934 | 0.72 | GABRA5 (0.49) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL7564375 | 0.72 | ALDH1A1 (0.38) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL1417466 | 0.72 | GABRA5 (0.47) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E | |
| SCHEMBL10401135 | 0.71 | HSD17B10 (0.37) | HSD17B10GABRA5GABRB2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919939-A | Preparation of cephem and isooxacephem derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-07-06 | — | — | US | disclosed |
| US-5883247-A | ACYLATION WITH AMINOTHIAZOLE DERIVATIVE ACTIVATED AS MIXED ANHYDRIDE OF THIOPHOSPHORIC ACID | HOFFMANN-LA ROCHE INC. (US) | 1999-03-16 | — | — | US | disclosed |