Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 5/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379883 | 0.89 | PTPN1 (0.61) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL7409389 | 0.88 | CTSS (0.65) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL7409385 | 0.88 | CTSS (0.65) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL22404737 | 0.86 | CTSS (0.64) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL85543 | 0.86 | CTSS (0.64) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL3355326 | 0.86 | CTSS (0.64) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL23729806 | 0.85 | CTSS (0.58) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL3826349 | 0.84 | CTSS (0.66) | PTPN1CTSSCTSKCTSBCTSL | |
| SCHEMBL7235877 | 0.84 | CTSS (0.63) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL1486267 | 0.84 | CTSS (0.63) | CTSSCTSKCTSBCTSLPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901628-A1 | PHOSPHOTYROSINE MIMICS AND METHODS FOR IDENTIFYING AND USING SAME | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997042501-A1 | PHOSPHOTYROSINE MIMICS AND METHODS FOR IDENTIFYING AND USING SAME | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-11-13 | — | — | WO | disclosed |