Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | CTSS | P25774 | 4/20 | 0.57 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | MME | P08473 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378902 | 0.89 | PTPN1 (0.54) | PTPN1ACECTSSCTSKCTSL | |
| SCHEMBL1325182 | 0.87 | CTSS (0.72) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL1325181 | 0.87 | CTSS (0.72) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL1326276 | 0.87 | CTSS (0.72) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL13227703 | 0.86 | PTPN1 (0.63) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL3728076 | 0.85 | PTPN1 (0.62) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL3728073 | 0.85 | PTPN1 (0.62) | PTPN1ACECTSSCTSKITGB3 | |
| SCHEMBL3724246 | 0.84 | ITGA4 (0.63) | PTPN1ACEITGA4ITGB7 | |
| SCHEMBL3724244 | 0.84 | ITGA4 (0.63) | PTPN1ACEITGA4ITGB7 | |
| SCHEMBL6169830 | 0.83 | PTPN1 (0.60) | PTPN1ACECTSSCTSKITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901628-A1 | PHOSPHOTYROSINE MIMICS AND METHODS FOR IDENTIFYING AND USING SAME | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997042501-A1 | PHOSPHOTYROSINE MIMICS AND METHODS FOR IDENTIFYING AND USING SAME | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-11-13 | — | — | WO | disclosed |