Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.38 |
| ▸ | ABL1 | P00519 | 15/20 | 0.38 |
| ▸ | HCK | P08631 | 14/20 | 0.38 |
| ▸ | EGFR | P00533 | 14/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.38 |
| ▸ | MTOR | P42345 | 13/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 13/20 | 0.38 |
| ▸ | PRKDC | P78527 | 13/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 13/20 | 0.38 |
| ▸ | KDR | P35968 | 12/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.38 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.35 |
| ▸ | CSK | P41240 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25793185 | 0.78 | POLB (0.43) | SRCABL1HCKEGFRPIK3CB | |
| SCHEMBL21641320 | 0.77 | SRC (0.39) | SRCABL1HCKEGFRMPO | |
| SCHEMBL19086974 | 0.72 | — | — | |
| SCHEMBL2817008 | 0.72 | PIK3CG (0.38) | SRCABL1HCKEGFRPIK3CB | |
| SCHEMBL21641026 | 0.72 | HTR2C (0.46) | SRCABL1 | |
| SCHEMBL25719251 | 0.72 | MPO (0.35) | SRCABL1HCKEGFRPIK3CB | |
| SCHEMBL25516557 | 0.72 | TGFBR1 (0.43) | MPO | |
| Hydrochloric Acid SCHEMBL31714233 | 0.71 | NOS3 (0.32) | — | |
| SCHEMBL26151381 | 0.71 | ABL1 (0.33) | SRCABL1HCKEGFRPIK3CB | |
| SCHEMBL8375126 | 0.71 | SRC (0.48) | SRCABL1HCKEGFRPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900206-A1 | NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS | L'OREAL (FR) | 1999-03-10 | — | — | EP | claimed |
| WO-1997042173-A1 | NEW DIAMINO PYRAZOLS, THEIR SYNTHESIS, KERATIN FIBRE DYEING COMPOSITIONS CONTAINING THEM, KERATIN FIBRE DYEING METHODS | L'OREAL (FR) | 1997-11-13 | — | — | WO | claimed |