Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379982 | 1.00 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1KDM4E | |
| SCHEMBL3054458 | 0.82 | KDM4E (0.55) | TSHRALDH1A1MAPK1TDP1KDM4E | |
| SCHEMBL4305909 | 0.82 | KDM4E (0.55) | TSHRALDH1A1MAPK1TDP1KDM4E | |
| SCHEMBL8376938 | 0.82 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1CA12 | |
| SCHEMBL8376937 | 0.82 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1CA12 | |
| SCHEMBL490074 | 0.80 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1CA12 | |
| SCHEMBL30414359 | 0.80 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1CA12 | |
| SCHEMBL490075 | 0.80 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1CA12 | |
| SCHEMBL490611 | 0.77 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1ALOX15 | |
| SCHEMBL8373322 | 0.77 | TSHR (0.50) | TSHRALDH1A1MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883211-A | Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis | ACLARA BIOSCIENCES, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| WO-1997040078-A1 | THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS | SOANE BIOSCIENCES (US) | 1997-10-30 | — | — | WO | disclosed |