Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490612 | 1.00 | TSHR (0.41) | TSHRKMT2AALOX15BLMPMP22 | |
| SCHEMBL8185221 | 0.87 | KMT2A (0.47) | TSHRKMT2AALOX15BLMPMP22 | |
| SCHEMBL23390991 | 0.87 | FOLH1 (0.44) | TSHRKMT2ABLMCA1CYP2C19 | |
| SCHEMBL8185224 | 0.87 | KMT2A (0.47) | TSHRKMT2AALOX15BLMPMP22 | |
| SCHEMBL490075 | 0.81 | TSHR (0.43) | TSHRKMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL490074 | 0.81 | TSHR (0.43) | TSHRKMT2AALDH1A1MAPK1TDP1 | |
| SCHEMBL8374067 | 0.79 | HPGDS (0.42) | TSHRALDH1A1MAPK1TDP1CA1 | |
| SCHEMBL8374065 | 0.79 | HPGDS (0.42) | TSHRALDH1A1MAPK1TDP1CA1 | |
| SCHEMBL8376938 | 0.79 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1CA2 | |
| SCHEMBL8376937 | 0.79 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190011442-A1 | METHOD FOR DETECTING SUBSTANCE OF INTEREST, METHOD FOR QUANTIFYING SUBSTANCE OF INTEREST, KIT, AND METHOD FOR PREPARING REAGENT | FURUKAWA ELECTRIC CO., LTD. (JP) | 2019-01-10 | — | — | US | disclosed |
| US-20180348228-A1 | Method of Determining Quantity of Objects to be Detected in Specimen | ORTHO CLINICAL DIAGNOSTICS KK (JP) | 2018-12-06 | — | — | US | disclosed |
| US-8105503-B2 | Method of storing thermoresponsive polymer in state of aqueous solution | CHISSO CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-8105493-B2 | Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit | JNC CORPORATION (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20110233453-A1 | METHOD OF STORING THERMORESPONSIVE POLYMER IN STATE OF AQUEOUS SOLUTION | CHISSO CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
| US-7976728-B2 | Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same | JNC CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| EP-2009044-B1 | Method of storing an aqueous dispersion of particle modified with a polymer having upper critical solution temperature | JNC CORP (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-20090001321-A1 | AQUEOUS SOLUTION OF POLYMER HAVING UPPER CRITICAL SOLUTION TEMPERATURE, AQUEOUS DISPERSION OF PARTICLE MODIFIED WITH THE POLYMER AND METHOD OF STORING THE SAME | CHISSO CORPORATION (JP) | 2009-01-01 | — | — | US | disclosed |
| US-20090001025-A1 | AGGREGATION AND DISPERSION METHODS OF MAGNETIC PARTICLES, SEPARATION AND DETECTION METHODS USING THE SAME AND DETECTION KIT | CHISSO CORPORATION (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2009044-A1 | Aqueous solution of polymer having upper critical solution temperature, aqueous dispersion of particle modified with the polymer and method of storing the same | Chisso Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2009442-A2 | Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit | Chisso Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-5883211-A | Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis | ACLARA BIOSCIENCES, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| WO-1997040078-A1 | THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS | SOANE BIOSCIENCES (US) | 1997-10-30 | — | — | WO | disclosed |