Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380230 | 1.00 | MAPT (0.44) | MAPTMAPK1KDM4EKMT2AIDE | |
| SCHEMBL7883529 | 0.84 | ALDH1A1 (0.53) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL7883531 | 0.84 | ALDH1A1 (0.53) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL4137698 | 0.81 | KMT2A (0.40) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL4137696 | 0.81 | KMT2A (0.40) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL9178354 | 0.79 | NPC1 (0.54) | MAPTMAPK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9178347 | 0.79 | NPC1 (0.54) | MAPTMAPK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15189810 | 0.75 | MEN1 (0.39) | MAPTMAPK1KDM4EKMT2AMEN1 | |
| SCHEMBL19030395 | 0.72 | MAPT (0.50) | MAPTMAPK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1099792 | 0.72 | ALDH1A1 (0.42) | MAPTMAPK1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962484-A | SUNSCREEN COSMETICS | SOCIETE L'OREAL S.A. (FR) | 1999-10-05 | — | — | US | disclosed |
| EP-0708108-B1 | Solar filtres, cosmetic sunscreen compositions containing them, and their application | OREAL (FR) | 1997-11-12 | — | — | EP | disclosed |
| US-5663270-A | Photoprotective/cosmetic compositions comprising substituted polyorganosiloxanes/polyorganosilanes | L'OREAL (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0708108-A1 | Solar filtres, cosmetic sunscreen compositions containing them, and their application | L'OREAL (FR) | 1996-04-24 | — | — | EP | disclosed |