Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4117143 | 1.00 | CTSK (0.51) | CTSKCTSSAPPCA1CA2 | |
| SCHEMBL4117141 | 1.00 | CTSK (0.51) | CTSKCTSSAPPCA1CA2 | |
| SCHEMBL3184905 | 1.00 | CTSK (0.51) | CTSKCTSSAPPCA1CA2 | |
| SCHEMBL30641554 | 0.93 | KLK5 (0.48) | CTSKCTSSAPPCA1CA2 | |
| SCHEMBL18938358 | 0.92 | CTSS (0.48) | CTSKCTSSAPPPPARAPPARG | |
| SCHEMBL9854732 | 0.89 | CTSS (0.46) | CTSKCTSSAPPATM | |
| SCHEMBL23158638 | 0.88 | CTSK (0.49) | CTSKCTSSAPPGABRB1GABRB2 | |
| SCHEMBL8895040 | 0.88 | KLK5 (0.51) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL8231291 | 0.88 | KLK5 (0.51) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL12069801 | 0.88 | KLK5 (0.51) | CTSKCTSSGABRB1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425212-B1 | Cyclic anti-aggregatory peptides | SMITHKLINE BEECHAM CORP (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0425212-A2 | Cyclic anti-aggregatory peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |