Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069801 | 1.00 | KLK5 (0.51) | KLK5CTSKCTSSMAPTKMT2A | |
| SCHEMBL8231291 | 1.00 | KLK5 (0.51) | KLK5CTSKCTSSMAPTKMT2A | |
| SCHEMBL30641554 | 0.96 | KLK5 (0.48) | KLK5CTSKCTSSMAPTKMT2A | |
| SCHEMBL18938357 | 0.92 | KLK5 (0.47) | KLK5CTSKCTSSMAPTCTSL | |
| SCHEMBL8380269 | 0.88 | CTSK (0.51) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL4117141 | 0.88 | CTSK (0.51) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL4117143 | 0.88 | CTSK (0.51) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL3184905 | 0.88 | CTSK (0.51) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL15312814 | 0.88 | CTSK (0.46) | KLK5CTSKCTSSMAPTGABRB1 | |
| SCHEMBL15312812 | 0.88 | CTSK (0.46) | KLK5CTSKCTSSMAPTGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222546-A1 | METHODS FOR THE PREPARATION OF FUNCTIONALIZED PEPTIDES, PROTEINS AND CARBOHYDRATES AND THEIR CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-02 | — | — | US | disclosed |
| US-7781609-B2 | Process for producing optically active β-hydroxy-α-aminocarboxylic acid derivative | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20080139825-A1 | Process For Producing Optically Active Beta-Hydroxy-Alpha-Aminocarboxylic Acid Derivative | NISSAN CHEMICAL INDUSTRIAL, LTD. (JP) | 2008-06-12 | — | — | US | disclosed |
| US-5643872-A | ANTIAGGLOMERANTS FOR PLATELETS, ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139825-A1 | Process For Producing Optically Active Beta-Hydroxy-Alpha-Aminocarboxylic Acid Derivative | HCAR2, HCAR1, ALDH7A1 | KLK5 2969/4885CTSK 1882/4885CTSS 1136/4885 |
| US-20100222546-A1 | METHODS FOR THE PREPARATION OF FUNCTIONALIZED PEPTIDES, PROTEINS AND CARBOHYDRATES AND THEIR CONJUGATES | PTMS, STT3A, GCG | KLK5 574/4885CTSK 1454/4885CTSS 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.