Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL647935 | 0.97 | TP53 (0.34) | TP53 | |
| SCHEMBL615604 | 0.80 | TP53 (0.33) | TP53 | |
| SCHEMBL1135083 | 0.80 | TP53 (0.33) | TP53 | |
| SCHEMBL28338994 | 0.79 | TP53 (0.32) | TP53 | |
| SCHEMBL4577140 | 0.78 | — | — | |
| SCHEMBL9066142 | 0.77 | TP53 (0.31) | TP53 | |
| SCHEMBL6850854 | 0.77 | SIGMAR1 (0.31) | TP53 | |
| Toluene SCHEMBL28914526 | 0.75 | LMNA (0.37) | — | |
| Hydrochloric Acid SCHEMBL7205530 | 0.72 | MAPT (0.31) | — | |
| SCHEMBL7171976 | 0.72 | LTA4H (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916982-A | Process for the production of polyolefins | NIPPON OIL CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |
| EP-0768320-A1 | Catalyst component and catalyst | NIPPON OIL CO. LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |
| EP-0768319-A1 | Process for the production of polyolefins | NIPPON OIL CO. LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |