Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | TFEB | P19484 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477126 | 0.89 | KDM4E (0.60) | PTGER3PTGER4PTGER2PTGER1SMN1; SMN2 | |
| SCHEMBL10477123 | 0.89 | KDM4E (0.60) | PTGER3PTGER4PTGER2PTGER1SMN1; SMN2 | |
| SCHEMBL3340127 | 0.87 | PTGER3 (0.62) | PTGER3PTGER4PTGER2PTGER1GAA | |
| SCHEMBL2292426 | 0.87 | PTGER3 (0.62) | PTGER3PTGER4PTGER2PTGER1GAA | |
| SCHEMBL3235018 | 0.80 | ALDH1A1 (0.62) | GAAHTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14843147 | 0.80 | PTGER1 (0.64) | PTGER3PTGER4PTGER2PTGER1GAA | |
| SCHEMBL1356220 | 0.80 | PTGER1 (0.64) | PTGER3PTGER4PTGER2PTGER1GAA | |
| SCHEMBL10407861 | 0.79 | NFE2L2 (0.47) | PTGER3PTGER4PTGER2GAANFE2L2 | |
| SCHEMBL10407860 | 0.79 | NFE2L2 (0.47) | PTGER3PTGER4PTGER2GAANFE2L2 | |
| SCHEMBL7951999 | 0.79 | ALDH1A1 (0.40) | GAASMN1; SMN2KDM4EMAPTPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |