SCHEMBL7951999

SCHEMBL7951999

COCCOCOc1cc(Cl)c(/C=C/C(=O)O)cc1OCOCCOC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
RARG P13631 2/20 0.38
IKBKB O14920 1/20 0.38
RARA P10276 1/20 0.38
POLB P06746 1/20 0.37
KDM4E B2RXH2 4/20 0.36
PLA2G1B P04054 1/20 0.36
MAPT P10636 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
GAA P10253 2/20 0.36
DPP4 P27487 2/20 0.35
F2 P00734 1/20 0.35
ELANE P08246 1/20 0.35
HTR1A P08908 1/20 0.35
HPGD P15428 1/20 0.35
HTR2C P28335 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7952003 1.00 ALDH1A1 (0.40) ALDH1A1KMT2AMEN1RARGIKBKB
SCHEMBL7966397 0.84 IKBKB (0.38) ALDH1A1KMT2AMEN1RARGIKBKB
SCHEMBL8155643 0.82 KDM4E (0.39) ALDH1A1RARGIKBKBRARAKDM4E
SCHEMBL7963270 0.81 ALDH1A1 (0.51) ALDH1A1KMT2AMEN1RARGPOLB
SCHEMBL7964173 0.79 RARA (0.38) ALDH1A1KMT2AMEN1RARGIKBKB
SCHEMBL7964175 0.79 RARA (0.38) ALDH1A1KMT2AMEN1RARGIKBKB
SCHEMBL8380440 0.79 PTGER3 (0.56) KDM4EPLA2G1BMAPTATG4BGAA
SCHEMBL7964222 0.78 ALDH1A1 (0.36) ALDH1A1RARGPOLBKDM4E
SCHEMBL9181364 0.78 KDM4E (0.61) ALDH1A1KMT2AMEN1IKBKBRARA
SCHEMBL9181354 0.78 KDM4E (0.61) ALDH1A1KMT2AMEN1IKBKBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313305-B1 ANTIBIOTICS, BACTERICIDES HOECHST MARION ROUSSEL (FR) 2001-11-06 US disclosed
US-5883248-A QUATERNARY AMMONIUM INTERMEDIATES ROUSSEL UCLAF (FR) 1999-03-16 US disclosed
US-5763617-A Cephalosporins ROUSSEL UCLAF (FR) 1998-06-09 US disclosed
US-5728828-A A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS ROUSSEL UCLAF (FR) 1998-03-17 US disclosed
US-5712266-A Cephalosporins ROUSSEL UCLAF (FR) 1998-01-27 US disclosed
US-5587372-A BACERICIDES ROUSSEL UCLAF (FR) 1996-12-24 US disclosed