Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457034 | 0.81 | TSHR (0.54) | HPGDTSHRPOLBTDP1SMN1; SMN2 | |
| SCHEMBL27876289 | 0.79 | TSHR (0.52) | HPGDTSHRPOLBTDP1SMN1; SMN2 | |
| SCHEMBL27892981 | 0.79 | TSHR (0.52) | HPGDTSHRPOLBTDP1SMN1; SMN2 | |
| SCHEMBL514995 | 0.75 | TSHR (0.69) | TSHRTDP1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL6207375 | 0.75 | TSHR (0.47) | HPGDTSHRTDP1SMN1; SMN2GAA | |
| SCHEMBL6206058 | 0.75 | TSHR (0.47) | HPGDTSHRTDP1SMN1; SMN2GAA | |
| SCHEMBL16655482 | 0.74 | SMN1; SMN2 (0.46) | TSHRPOLBSMN1; SMN2GAAKMT2A | |
| Ammonia Solution, Strong SCHEMBL27732716 | 0.74 | TSHR (0.67) | TSHRTDP1SMN1; SMN2KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL28478926 | 0.74 | TSHR (0.67) | TSHRTDP1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL28740463 | 0.73 | KMT2A (0.53) | HPGDTSHRPOLBTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |