Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14422937 | 0.90 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTCYP1A2POLB | |
| SCHEMBL14423157 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTCYP1A2POLB | |
| SCHEMBL10533804 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTPOLBKDM4E | |
| SCHEMBL362773 | 0.77 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTCYP1A2POLB | |
| SCHEMBL14971234 | 0.77 | KDM4E (0.36) | ALDH1A1SMN1; SMN2MAPTKDM4ELMNA | |
| SCHEMBL1645065 | 0.77 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTCYP1A2POLB | |
| SCHEMBL14423158 | 0.74 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL428797 | 0.73 | KDM4E (0.37) | ALDH1A1SMN1; SMN2MAPTCYP1A2KDM4E | |
| SCHEMBL4073329 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2MAPTPOLBTSHR | |
| SCHEMBL15314335 | 0.73 | FAAH (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | claimed |