Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596509 | 0.89 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL11552290 | 0.80 | CNR1 (0.68) | ESR1ESR2 | |
| SCHEMBL11548984 | 0.80 | CNR1 (0.68) | ESR1ESR2 | |
| SCHEMBL6594160 | 0.78 | TUBB4A (0.59) | ESR1ESR2 | |
| SCHEMBL7101796 | 0.77 | ESR1 (0.50) | ESR1ESR2 | |
| SCHEMBL7101127 | 0.76 | ESR1 (0.56) | ESR1 | |
| SCHEMBL16346479 | 0.76 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL7927545 | 0.76 | ESR1 (0.50) | ESR1ESR2 | |
| SCHEMBL7102038 | 0.75 | ESR1 (0.55) | ESR1 | |
| SCHEMBL6440449 | 0.75 | ESR1 (0.48) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919800-A | INHIBITING ENDOMETRIOSIS BY ADMISTERING (6-HYDROXY-3-(4-(2-(1-PIPERIDINYL)ETHOXY)PHENOXY)-2-(4-METHOXYPHENYL))BENZO B)THIOPHENE OR THE HYDROCHLORIDE SALT THEREOF | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5856339-A | POST-MENOPAUSAL SYNDROME, AND UTERINE FIBROID DISEASE, ENDOMETRIOSIS, AND AORTAL SMOOTH MUSCLE CELL PROLIFERATION. | ELI LILLY AND COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| US-5856340-A | 2-PHENYL-3-/ALKOXYPHENOXY OR PHENYLTHIO/BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| US-5723474-A | TREATING POST-MENOPAUSAL SYNDROME, UTERINE FIBROID DISEASE, ENDOMETRIOSIS, AND AORTAL SMOOTH MUSCLE CELL PROLIFERATION; ANTIESTROGENS | ELI LILLY AND COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| US-5510357-A | POST-MENOPAUSAL SYNDROME, ENDOMETRIOSIS | ELI LILLY AND COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5510498-A | Benzothiophene compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| US-5510358-A | OSTEOPOROSIS | ELI LILLY AND COMPANY (US) | 1996-04-23 | — | — | US | disclosed |