Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348701 | 0.84 | ESR1 (0.42) | ESR1ESR2KDM4EGLAMAPT | |
| SCHEMBL6594160 | 0.83 | TUBB4A (0.59) | ESR1ESR2KDM4EMAPTKMT2A | |
| SCHEMBL6596509 | 0.83 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL7101796 | 0.77 | ESR1 (0.50) | ESR1ESR2L3MBTL1TUBB4ATUBB | |
| SCHEMBL28348129 | 0.76 | MAPT (0.44) | KDM4EGLAMAPTKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6550274 | 0.76 | ESR1 (0.74) | ESR1ESR2ITGA4LTA4H | |
| Hydrochloric Acid SCHEMBL6551013 | 0.75 | ESR1 (0.70) | ESR1ESR2ITGA4LTA4H | |
| SCHEMBL8380746 | 0.75 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL26724808 | 0.73 | LTA4H (0.39) | ESR1ESR2KDM4EGLAMAPT | |
| SCHEMBL16346286 | 0.73 | ESR1 (0.63) | ESR1ESR2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054882-A1 | Diaryl ether condensation reactions | NSF - DEITR | 2005-03-10 | — | — | US | disclosed |
| US-6762329-B2 | EFFECTS OF ACIDIC ACTIVATORS ON ULLMANN-TYPE COUPLINGS INVOLVING ELECTRON-POOR AND/OR RELATIVELY INSOLUBLE SUBSTRATES. | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-07-13 | — | — | US | disclosed |
| US-20030088128-A1 | Diaryl ether condensation reactions | NATIONAL SCIENCE FOUNDATION | 2003-05-08 | — | — | US | disclosed |
| US-6395939-B1 | CATALYTIC ETHERIFICATION AND CONDENSATION WITH COPPER CATALYSTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054882-A1 | Diaryl ether condensation reactions | NSFL1C, DERL1, UBE2M | ESR1 444/4885ESR2 959/4885KDM4E 1568/4885 |
| US-20030088128-A1 | Diaryl ether condensation reactions | NSFL1C, DERL1, UBE2M | ESR1 444/4885ESR2 959/4885KDM4E 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.