Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906619 | 0.95 | ITGB3 (0.47) | ITGB3ITGA2BEPHX2TMPRSS2GAA | |
| SCHEMBL8384345 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2BTMPRSS2LMNAGAA | |
| SCHEMBL7907920 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2BTMPRSS2LMNAHTT | |
| SCHEMBL7913438 | 0.87 | GAA (0.43) | ITGB3ITGA2BTMPRSS2LMNAGAA | |
| SCHEMBL8381648 | 0.86 | EPHX2 (0.49) | ITGB3ITGA2BEPHX2LMNAGAA | |
| SCHEMBL7906618 | 0.85 | HTT (0.49) | ITGB3ITGA2BTMPRSS2HTTMEN1 | |
| SCHEMBL8382592 | 0.83 | HTT (0.41) | ITGB3ITGA2BEPHX2LMNAHTT | |
| SCHEMBL8380840 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BTMPRSS2LMNAHTT | |
| SCHEMBL8381689 | 0.82 | EPHX2 (0.53) | ITGB3ITGA2BEPHX2TMPRSS2LMNA | |
| SCHEMBL7900135 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2BTMPRSS2HTTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |