Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913438 | 0.91 | GAA (0.43) | ITGB3ITGA2BALDH1A1TMPRSS2SMN1; SMN2 | |
| SCHEMBL7907920 | 0.90 | ITGB3 (0.53) | ITGB3ITGA2BALDH1A1TMPRSS2TP53 | |
| SCHEMBL8384345 | 0.90 | ITGB3 (0.40) | ITGB3ITGA2BALDH1A1TMPRSS2SMN1; SMN2 | |
| SCHEMBL8384256 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8386175 | 0.85 | CA12 (0.41) | ITGB3ITGA2BALDH1A1TMPRSS2TP53 | |
| SCHEMBL7906619 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1TMPRSS2TP53 | |
| SCHEMBL7906618 | 0.84 | HTT (0.49) | ITGB3ITGA2BALDH1A1TMPRSS2SMN1; SMN2 | |
| SCHEMBL8380937 | 0.83 | ITGB3 (0.46) | ITGB3ITGA2BTMPRSS2MEN1KMT2A | |
| SCHEMBL8386238 | 0.82 | HTT (0.43) | ALDH1A1SMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL8384540 | 0.82 | NPC1 (0.46) | MAPK1MAPTTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |