Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | GABRD | O14764 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | UBE2M | P61081 | 1/20 | 0.49 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14538230 | 0.97 | HPGD (0.71) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL7130857 | 0.85 | HPGD (0.83) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL14238822 | 0.85 | HPGD (0.83) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| Ethylene SCHEMBL8518039 | 0.84 | HPGD (0.64) | HPGDKDM4EUBE2MDCUN1D1 | |
| SCHEMBL1753626 | 0.82 | HPGD (0.97) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL2667152 | 0.82 | HPGD (0.90) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| Ethylene SCHEMBL8380995 | 0.81 | PKM (0.61) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL10174633 | 0.81 | HPGD (1.00) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL12969 | 0.81 | HPGD (1.00) | HPGDGABRDGABRA1GABRB1GABRA5 | |
| SCHEMBL8360507 | 0.80 | HPGD (0.73) | HPGDGABRDGABRA1GABRB1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |