Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446390 | 0.96 | PKM (0.65) | PKMALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13211827 | 0.90 | ALDH1A1 (0.57) | PKMALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL24120195 | 0.87 | HPGD (0.61) | PKMALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14817953 | 0.84 | ALDH1A1 (0.62) | PKMALDH1A1HPGDMEN1KMT2A | |
| Ethylene SCHEMBL8381019 | 0.84 | MTHFD2 (0.51) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL10726712 | 0.83 | ALDH1A1 (0.84) | PKMALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4557193 | 0.83 | ALDH1A1 (0.84) | PKMALDH1A1HPGDMEN1KMT2A | |
| Ethylene SCHEMBL8379754 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| Ethylene SCHEMBL8378361 | 0.83 | HPGD (0.66) | ALDH1A1HPGDKMT2ALMNAHSD11B1 | |
| Ethylene SCHEMBL8518039 | 0.83 | HPGD (0.64) | PKMALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |