Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21546007 | 0.86 | L3MBTL1 (0.55) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL6539750 | 0.85 | HTT (0.65) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL4415350 | 0.84 | HTT (0.75) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL27898281 | 0.82 | L3MBTL1 (0.66) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL6539802 | 0.82 | HTT (0.58) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL9574717 | 0.82 | HTT (0.73) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL29687865 | 0.82 | ALDH1A1 (0.65) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL21526676 | 0.82 | ALDH1A1 (0.56) | HTTALDH1A1TDP1KMT2ANPSR1 | |
| SCHEMBL8379922 | 0.81 | ALDH1A1 (0.56) | HTTALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL3316012 | 0.81 | KDM4E (0.65) | HTTALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781275-B2 | Polymerizable monomers and method of polymerizing the same | ALIGN TECHNOLOGY, INC. (US) | 2020-09-22 | — | — | US | disclosed |
| US-10781274-B2 | Polymerizable monomers and method of polymerizing the same | ALIGN TECHNOLOGY, INC. (US) | 2020-09-22 | — | — | US | disclosed |
| US-20200040113-A1 | POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME | ALIGN TECHNOLOGY, INC. | 2020-02-06 | — | — | US | disclosed |
| US-20190345276-A1 | POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME | TU WIEN (AT) | 2019-11-14 | — | — | US | disclosed |
| US-5976558-A | Silicone-containing derivatives of salicylic acid which have desquamating properties | L'OREAL (FR) | 1999-11-02 | — | — | US | disclosed |
| US-5906812-A | USEFUL FOR TREATING INTRISIC AND EXTRINSIC AGING SUCH AS WRINKLES, FINE LINES, ACTINIC BLEMISHES, DYSCHROMIAS, DERMATITIS OR SCARS IN HUMAN SKIN; COSMETICS | L'OREAL (FR) | 1999-05-25 | — | — | US | disclosed |
| US-5900231-A | COSMETIC AND/OR DERMATOLOGICAL SKIN TREATMENT | L'OREAL (FR) | 1999-05-04 | — | — | US | disclosed |
| US-5756485-A | TOPICAL APPLICATION TO PREVENT AGING | L'OREAL (FR) | 1998-05-26 | — | — | US | disclosed |