Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381731 | 0.84 | ALDH1A1 (0.43) | TNFRSF1AALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL8378667 | 0.84 | ALDH1A1 (0.43) | TNFRSF1AALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL7787864 | 0.81 | FDPS (0.45) | TNFRSF1AALDH1A1TDP1TUBB1FDPS | |
| SCHEMBL8382228 | 0.80 | PRKDC (0.42) | TNFRSF1AALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL8377236 | 0.80 | FDPS (0.39) | TNFRSF1AALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL8377250 | 0.80 | FDPS (0.39) | TNFRSF1AALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL20982737 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4ETSHRTDP1TUBB1 | |
| SCHEMBL3751505 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ETSHRTDP1TUBB1 | |
| SCHEMBL8652617 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KDM4ETSHRTDP1TUBB1 | |
| SCHEMBL7467304 | 0.78 | FDPS (0.57) | TNFRSF1AALDH1A1TSHRTDP1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883248-A | QUATERNARY AMMONIUM INTERMEDIATES | ROUSSEL UCLAF (FR) | 1999-03-16 | — | — | US | disclosed |
| US-5763617-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5728828-A | A 3-(3-CHLORO- OR IODOPROP-1-EN-1-YL),7-(2-AMINOTHIAZOL-4-YL) ((CARBOXY)(PHENYL)METHOXYIMINO)ACETAMIDO-3-CEPHEM; GRAMNEGATIVE AND -POSITIVE BACTERIA, ESP. ANTIBIOTIC-RESISTANCE STAPHYLOCOCCUS | ROUSSEL UCLAF (FR) | 1998-03-17 | — | — | US | disclosed |
| US-5712266-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1998-01-27 | — | — | US | disclosed |